Plasma proteome analysis for anti-obesity and anti-diabetic potentials of chitosan oligosaccharides in ob/ob mice.

@article{Kumar2009PlasmaPA,
  title={Plasma proteome analysis for anti-obesity and anti-diabetic potentials of chitosan oligosaccharides in ob/ob mice.},
  author={Suresh G. Kumar and Md Atiar Rahman and Sung Hak Lee and Hee Sun Hwang and Hyun Ah Kim and Jong Won Yun},
  journal={Proteomics},
  year={2009},
  volume={9 8},
  pages={2149-62}
}
Altered levels of adipokines, derived as a result of distorted adipocytes, are the major factors responsible for changing biochemical parameters in obesity that leads to the development of metabolic disorders such as insulin resistance and atherosclerosis. In our previous reports, chitosan oligosaccharides (CO) were proved to inhibit the differentiation of 3T3-L1 adipocytes. In the present study, an attempt was made to investigate the anti-obesity and anti-diabetic effect of CO on ob/ob mice… CONTINUE READING

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