Plasma protein binding and interaction studies with piroxicam

  title={Plasma protein binding and interaction studies with piroxicam},
  author={Zdena Trnavsk{\'a} and Karel Trnavsk{\'y}},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
The binding of non-steroidal antirheumatic drug piroxicam to human serum albumin, human plasma and serum has been studied by equilibrium dialysis at 22°C, pH 7.4. The binding data were analyzed according to Scatchard model. The values of binding parameters obtained for human serum albumin are quite similar to those obtained for human plasma and serum (N 1=0… CONTINUE READING