Plasma prekallikrein: a risk marker for hypertension and nephropathy in type 1 diabetes.

@article{Jaffa2003PlasmaPA,
  title={Plasma prekallikrein: a risk marker for hypertension and nephropathy in type 1 diabetes.},
  author={Ayad A. Jaffa and R Durazo-arvizu and Deyi Zheng and Daniel T. Lackland and Sujata Srikanth and W Timothy Garvey and Alvin H Schmaier},
  journal={Diabetes},
  year={2003},
  volume={52 5},
  pages={1215-21}
}
The relevance and significance of the plasma kallikrein/kinin system as a risk factor for the development of vascular complications in diabetic patients was explored in a cross-sectional study. We measured the circulating levels of plasma prekallikrein (PK) activity, factor XII, and high-molecular weight kininogen in the plasma of 636 type 1 diabetic patients from the Diabetes Control and Complications Trial/Epidemiology and Diabetes Intervention and Complications Study cohort. The findings… CONTINUE READING
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