Plasma pepsinogens, nutrients, and diet in areas of Italy at varying gastric cancer risk.

@article{Palli1991PlasmaPN,
  title={Plasma pepsinogens, nutrients, and diet in areas of Italy at varying gastric cancer risk.},
  author={Domenico Palli and Adriano Decarli and Francesco Cipriani and David Forman and Dino Amadori and Claudio Avellini and Attilio Carlo Giacosa and Paolo Manca and Antonio Russo and Richard Salkeld},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  year={1991},
  volume={1 1},
  pages={45-50}
}
In a survey of 930 adults aged 35-74 years randomly sampled from the general population of four areas of Italy at different risks for gastric cancer (GC), plasma levels of pepsinogens (PGI and PGII) and fat-soluble vitamins were assayed. Pepsinogen levels were used to identify individuals with chronic atrophic gastritis (CAG). Severe CAG (PGI < or = 20 pg/liter) affected 5.8% of the population, but the prevalence rose with increasing age and declining social class. Severe CAG was 5 times more… CONTINUE READING