Plasma osteocalcin levels as a predictor of cardiovascular disease in older men and women: a population-based cohort study.

@article{Holvik2014PlasmaOL,
  title={Plasma osteocalcin levels as a predictor of cardiovascular disease in older men and women: a population-based cohort study.},
  author={Kristin Holvik and Natasja M. van Schoor and Elisabeth M. W. Eekhoff and Martin den Heijer and Dorly J. H. Deeg and Paul Th A M Lips and Renate T de Jongh},
  journal={European journal of endocrinology},
  year={2014},
  volume={171 2},
  pages={161-70}
}
OBJECTIVE The role of osteocalcin (OC) in cardiovascular disease (CVD) is unresolved. We aimed to study the association between plasma OC concentrations and the risk of non-fatal and fatal CVDs. We also aimed to investigate whether such an association, if present, would be mediated by established metabolic risk factors. DESIGN A population-based longitudinal cohort study. METHODS In 1995/1996, OC was determined in blood samples drawn from 1319 subjects aged 65-88 years participating in the… CONTINUE READING
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Package ‘survival’: survival analysis, including penalised likelihood. http://cran.r-project.org/web/packages/survival/survival 4/25/2012

  • TM Therneau
  • Last access on 15/03/2013
  • 2013

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