Plasma oestriol following vaginal administration: morning versus evening insertion and influence of food.

@article{Heimer1986PlasmaOF,
  title={Plasma oestriol following vaginal administration: morning versus evening insertion and influence of food.},
  author={G M Heimer and Donald E. Englund},
  journal={Maturitas},
  year={1986},
  volume={8 3},
  pages={239-43}
}
The aim of this trial was to study the vaginal absorption of oestriol and to investigate whether morning rather than evening oestriol administration would produce different plasma oestriol patterns. The influence of food intake on plasma oestriol levels was also investigated. Nine post-menopausal women were given 0.5 mg oestriol (ovula supplied by Leo AB, Sweden) intravaginally every evening for 16 days. Thereafter, 1 mg oestriol was given every evening for another 5 days, except on treatment… CONTINUE READING