Plasma nucleic acids in the diagnosis and management of malignant disease.

Abstract

BACKGROUND There is a need for development of molecular markers of cancer that can be used clinically for the detection, prognostication, and monitoring of cancer. Recently, there has been much interest in the potential use of nucleic acid markers in plasma and serum for this purpose. APPROACH We reviewed published literature up to 2002 on the topic, with… (More)

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