Plasma nitrite/nitrate levels: a new biomarker for pulmonary arterial hypertension?

Abstract

The role of endothelial-derived nitric oxide (NO) and its downstream signalling pathways in modulating vascular tone and remodelling has been one of the most intriguing areas of vascular biology over the last quarter of a century. Its identification as the endothelial-derived relaxing factor responsible for relaxation of vascular smooth muscle led to the… (More)
DOI: 10.1183/13993003.01542-2016

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