Plasma microRNAs serve as biomarkers of therapeutic efficacy and disease progression in hypertension-induced heart failure.

@article{Dickinson2013PlasmaMS,
  title={Plasma microRNAs serve as biomarkers of therapeutic efficacy and disease progression in hypertension-induced heart failure.},
  author={Brent A Dickinson and Hillary M. Semus and Rusty L. Montgomery and Christianna Stack and Paul A Latimer and Steven M Lewton and Joshua M. Lynch and Thomas G Hullinger and Anita G. Seto and Eva van Rooij},
  journal={European journal of heart failure},
  year={2013},
  volume={15 6},
  pages={650-9}
}
AIMS Recent studies have shown that microRNAs (miRNAs), besides being potent regulators of gene expression, can additionally serve as circulating biomarkers of disease. The aim of this study is to determine if plasma miRNAs can be used as indicators of disease progression or therapeutic efficacy in hypertension-induced heart disease. METHODS AND RESULTS In order to define circulating miRNAs that change during hypertension-induced heart failure and that respond to therapeutic treatment, we… CONTINUE READING

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