Plasma methionine sulfoxide in persons with familial Alzheimer's disease mutations.


BACKGROUND Convergent evidence suggests that oxidative stress plays a central role in the pathology of Alzheimer's disease (AD). We asked if consequently, oxidation of methionine residues to methionine sulfoxide (MetO) was increased in plasma proteins of persons carrying familial AD (FAD) mutations. METHODS Plasma was collected from 31 persons from… (More)
DOI: 10.1159/000338546

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