Plasma metabolites reveal distinct profiles associating with different metabolic risk factors in monozygotic twin pairs

@article{Muniandy2018PlasmaMR,
  title={Plasma metabolites reveal distinct profiles associating with different metabolic risk factors in monozygotic twin pairs},
  author={Maheswary Muniandy and Vidya Velagapudi and Antti Hakkarainen and J O Jesper Lundbom and Nina Lundbom and Aila M. Rissanen and Jaakko Kaprio and Kirsi Hannele Pietil{\"a}inen and Miina Ollikainen},
  journal={International Journal of Obesity},
  year={2018},
  pages={1-16}
}
Obesity is related to a myriad of cardiometabolic outcomes, each of which may have a specific metabolomic signature and a genetic basis. We identified plasma metabolites associating with different cardiometabolic risk factors (adiposity, cholesterol, insulin resistance, and inflammation) in monozygotic (MZ) twins. Additionally, we assessed if metabolite profiling can identify subgroups differing by cardiometabolic risk factors. We quantified 111 plasma metabolites (Acquity UPLC—triple… CONTINUE READING
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