Plasma metabolic fingerprinting of childhood obesity by GC/MS in conjunction with multivariate statistical analysis.

@article{Zeng2010PlasmaMF,
  title={Plasma metabolic fingerprinting of childhood obesity by GC/MS in conjunction with multivariate statistical analysis.},
  author={Maomao Zeng and Yi-Zeng Liang and Hongdong Li and Mei Wang and Bing Wang and Xian Zhong Chen and Neng Zhou and Dongsheng Cao and Jing Wu},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2010},
  volume={52 2},
  pages={265-72}
}
Metabolic fingerprinting is a powerful tool for exploring systemic metabolic perturbations and potential biomarkers, thus may shed light on the pathophysiological mechanism of diseases. In this work, a new strategy of metabolic fingerprinting was proposed to exploit the disturbances of metabolic patterns and biomarker candidates of childhood obesity. Plasma samples from children with normal weight, overweight and obesity were first profiled by GC/MS. ULDA (uncorrelated linear discriminant… CONTINUE READING

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