Plasma membrane polarization during mating in yeast cells

  title={Plasma membrane polarization during mating in yeast cells},
  author={Tomasz Jacek Pr{\'o}szyński and Robin W. Klemm and Michel Bagnat and Katharina Gaus and Kai Simons},
  journal={The Journal of Cell Biology},
  pages={861 - 866}
The yeast mating cell provides a simple paradigm for analyzing mechanisms underlying the generation of surface polarity. Endocytic recycling and slow diffusion on the plasma membrane were shown to facilitate polarized surface distribution of Snc1p (Valdez-Taubas, J., and H.R. Pelham. 2003. Curr. Biol. 13:1636-1640). Here, we found that polarization of Fus1p, a raft-associated type I transmembrane protein involved in cell fusion, does not depend on endocytosis. Instead, Fus1p localization to the… CONTINUE READING
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