Plasma membrane monoamine transporters: structure, regulation and function
@article{Torres2003PlasmaMM, title={Plasma membrane monoamine transporters: structure, regulation and function}, author={Gonzalo E. Torres and Raul R. Gainetdinov and Marc G. Caron}, journal={Nature Reviews Neuroscience}, year={2003}, volume={4}, pages={13-25} }
The classical biogenic amine neurotransmitters — dopamine, noradrenaline, and 5-hydroxytryptamine — control a variety of functions including locomotion, autonomic function, hormone secretion, and the complex behaviours that are associated with affect, emotion and reward. A key step that determines the intensity and duration of monoamine signalling at synapses is the reuptake of the released transmitter into nerve terminals through high-affinity plasma membrane transporters. In recent years…
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