Plasma membrane calcium pump activity in rat pancreatic islets

@article{Rossi2006PlasmaMC,
  title={Plasma membrane calcium pump activity in rat pancreatic islets},
  author={J. P. Rossi and Alejandro M Villamil and Mar{\'i}a Mercedes Echarte and Mar{\'i}a Eugenia Alzugaray and Mar{\'i}a I. Borelli and Mar{\'i}a Elisa Garc{\'i}a and Jyoti Pande and A. K. Grover and Juan Jos{\'e} Gagliardino},
  journal={Cell Biochemistry and Biophysics},
  year={2006},
  volume={46},
  pages={193-200}
}
The aim of this study was to quantify the glucose modulation of the plasma membrane calcium pump (PMCA) function in rat pancreatic islets. Ca2+-ATPase activity and levels of phosphorylated PMCA intermediates both transiently declined to a minimum in response to stimulation by glucose. Strictly dependent on Ca2+ concentration, this inhibitory effect was fully expressed at physiological concentrations of the cation (less than 0.5 μM), then progressively diminished at higher concentrations. These… CONTINUE READING

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Strictly dependent on Ca2 + concentration , this inhibitory effect was fully expressed at physiological concentrations of the cation ( less than 0.5 μM ) , then progressively diminished at higher concentrations .
Strictly dependent on Ca2 + concentration , this inhibitory effect was fully expressed at physiological concentrations of the cation ( less than 0.5 μM ) , then progressively diminished at higher concentrations .
Plasma membrane calcium pump activity in rat pancreatic islets .
Plasma membrane calcium pump activity in rat pancreatic islets .
The aim of this study was to quantify the glucose modulation of the plasma membrane calcium pump ( PMCA ) function in rat pancreatic islets .
The aim of this study was to quantify the glucose modulation of the plasma membrane calcium pump ( PMCA ) function in rat pancreatic islets .
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