Plasma macromolecules in interstitial fluid from normal and atherosclerotic human aorta.


The concentration of LDL free in the IF from normal intima is twice the concentration in the patients plasma. LDL is virtually excluded from media, thus it seems to be trapped between endothelium and the internal elastic lamina. Expressed as percent of plasma concentration, concentration of macromolecules in IF is directly related to molecular mass… (More)


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