Plasma lipoprotein changes in humans induced by beta-interferon.

@article{Rosenzweig1987PlasmaLC,
  title={Plasma lipoprotein changes in humans induced by beta-interferon.},
  author={I B Rosenzweig and Donald A. Wiebe and Ernest C. Borden and Barry E. Storer and Earl Shrago},
  journal={Atherosclerosis},
  year={1987},
  volume={67 2-3},
  pages={
          261-7
        }
}
Two groups of patients were administered either 4.5 X 10(6) U or 90 X 10(6) U each of recombinant DNA-derived interferon-beta serine (IFN-beta ser) i.v. daily for 10 days. IFN-beta ser affected lipoprotein lipids of patients in a dose dependent fashion. A decrease in plasma total cholesterol concentration occurred 24 h after therapy was initiated, regardless of dose. A dose-related decrease in plasma cholesterol concentration of 9% and 23% for patients on the low dose and high dose respectively… CONTINUE READING

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