Plasma levels of nitrite/nitrate and platelet cGMP levels are decreased in patients with atrial fibrillation.

@article{Minamino1997PlasmaLO,
  title={Plasma levels of nitrite/nitrate and platelet cGMP levels are decreased in patients with atrial fibrillation.},
  author={Tetsuo Minamino and Masafumi Kitakaze and Hiroki Sato and Hiroshi Asanuma and Hiroharu Funaya and Yukihiro Koretsune and Masatsugu Hori},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1997},
  volume={17 11},
  pages={3191-5}
}
Patients with atrial fibrillation have been reported to exhibit abnormal hemostasis. Since nitric oxide (NO) exerts antithrombotic effects and attenuates platelet function, we evaluated two indicators of plasma NO levels, the plasma levels of nitrite and nitrate (NOx), and the levels of cGMP in platelets. We also examined whether indicators of plasma NO levels were associated with abnormalities in parameters related to platelet function, blood coagulation, and fibrinolysis. We evaluated 45… CONTINUE READING

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