Plasma levels of atrial natriuretic peptide and tumor necrosis factor-α during transient myocardial ischemia in patients with stable angina

@article{Wiedermann1991PlasmaLO,
  title={Plasma levels of atrial natriuretic peptide and tumor necrosis factor-α during transient myocardial ischemia in patients with stable angina},
  author={Dr. C. J. Wiedermann and Franz J Wiedermann and Manfred Herold and Herbert Tilg and Nico Moes and Volker Muehlberger and H. Beimpold and Edgar Knapp},
  journal={Klinische Wochenschrift},
  year={1991},
  volume={69},
  pages={944-944}
}
Atrial natriuretic peptide (ANP), which is released from the myocardium upon certain hemodynamic changes, and tumor necrosis factor-c~ (TNF) released from vessel wall and circulating blood ceils, act directly as vasodilators [1, 4, 6]. Blood levels of ANP and TNF have been found to be significantly elevated in chronic heart failure [1, 3]. In man, coronary angioplasty (PTCA) provides a model to induce transient myocardial ischemia and to study the release of regulatory mediators. A preliminary… CONTINUE READING