Plasma levels of 7B2 (a novel pituitary polypeptide) and its molecular forms in plasma and urine in patients with chronic renal failure: possible degradation by the kidney.

@article{Iguchi1988PlasmaLO,
  title={Plasma levels of 7B2 (a novel pituitary polypeptide) and its molecular forms in plasma and urine in patients with chronic renal failure: possible degradation by the kidney.},
  author={Haruo Iguchi and Syunsuke Natori and Yangyan Ou and Hajime Nawata and Kiminori Kato and Hiroshi Ibayashi and Steven R. Bloom},
  journal={Regulatory peptides},
  year={1988},
  volume={21 3-4},
  pages={263-70}
}
Plasma immunoreactive (IR)-7B2 was measured in patients with chronic renal failure (CRF), using a specific radioimmunoassay. The mean (+/- S.E.M.) concentration of plasma IR-7B2 in CRF patients under hemodialysis (502 +/- 36 pg/ml, n = 27) was significantly higher than that in normal subjects (men, 52.9 +/- 1.7 pg/ml (n = 179); women, 55.8 +/- 1.3 pg/ml (n = 198]. Significant correlations between plasma levels of IR-7B2 and those of blood urea nitrogen, creatinine and beta 2-microglobulin were… CONTINUE READING