Plasma levels and urinary excretion of batroxobin and its defibrinogenating effects in various animal species.

@article{Sugai1986PlasmaLA,
  title={Plasma levels and urinary excretion of batroxobin and its defibrinogenating effects in various animal species.},
  author={Karlyn Sugai and Yorishige Imamura and S Mihashi and Masahiro Ohba and K Kunikane and Norio Mori and Shigeo Baba},
  journal={The Journal of toxicological sciences},
  year={1986},
  volume={11 2},
  pages={135-43}
}
The plasma levels and urinary excretion of batroxobin administered to 6 species of animals were examined by an enzyme immunoassay method. Defibrinogenating effect of batroxobin was also studied in those species. The plasma levels of immunoreactive batroxobin disappeared exponentially in all the animals and differences in half-life were observed to occur according to species. The elimination half-life of immunoreactive batroxobin in the plasma was the largest in dogs, followed by rats, monkeys… CONTINUE READING

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