Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone.

@article{Blum1997PlasmaLL,
  title={Plasma leptin levels in healthy children and adolescents: dependence on body mass index, body fat mass, gender, pubertal stage, and testosterone.},
  author={Werner F. Blum and Piera Englaro and S Hanitsch and A. Juul and Niels Thomas Hertel and J{\o}rn M{\"u}ller and Niels Erik Skakkebaek and Mark Louis Heiman and Martin Birkett and Andrea Attanasio and W. Kiess and Wolfgang Rascher},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1997},
  volume={82 9},
  pages={
          2904-10
        }
}
Leptin, the product of the ob gene, is thought to play a key role in the regulation of body fat mass. Beyond this function, it appears to be an integral component of various hypothalamo-pituitary-endocrine feedback loops. Because childhood and puberty are periods of major metabolic and endocrine changes, leptin levels and various hormonal parameters were investigated in a large cohort of healthy children and adolescents (312 males, 401 females, age 5.8-19.9 yr). For this purpose, a specific and… CONTINUE READING

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