Plasma kynurenine and related measures in tic disorder patients

  title={Plasma kynurenine and related measures in tic disorder patients},
  author={P. Hoekstra and G. Anderson and P. W. Troost and C. Kallenberg and R. Minderaa},
  journal={European Child & Adolescent Psychiatry},
  • P. Hoekstra, G. Anderson, +2 authors R. Minderaa
  • Published 2007
  • Psychology, Medicine
  • European Child & Adolescent Psychiatry
  • ObjectiveIncreased plasma kynurenine has been reported in tic disorder patients, and this observation has been suggested to be indicative of immune dysregulation. In the present study, we examined plasma levels of kynurenine and related molecules in a group of tic disorder patients.MethodsPlasma concentrations of tryptophan, kynurenine, cortisol, and neopterin were determined in Dutch tic disorder patients (N = 59), and healthy volunteers (N = 32). Group means were compared and age-controlled… CONTINUE READING
    21 Citations

    Figures, Tables, and Topics from this paper

    Altered monocyte activation markers in Tourette’s syndrome: a case–control study
    • 25
    • PDF
    Immune Dysfunction in Tourette Syndrome
    • 22
    • PDF
    The Modulating Role of Stress in the Onset and Course of Tourette’s Syndrome
    • 26
    • PDF
    Immunopathogenic mechanisms in tourette syndrome: A critical review
    • 114
    The role of immune mechanisms in Tourette syndrome
    • 52
    The Relationship between Tourette’s Syndrome and Infections
    • 10
    • PDF
    Association between intracellular infectious agents and Tourette’s syndrome
    • 23
    The immunobiology of Tourette's disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: a way forward.
    • 122
    • PDF


    Increased plasma kynurenine and its relationship to neopterin and tryptophan in Tourette's syndrome.
    • 31
    Blood serotonin and tryptophan in Tourette syndrome.
    • D. Comings
    • Medicine
    • American journal of medical genetics
    • 1990
    • 80
    • PDF
    Kynurenine potentiates the DOI head shake in mice
    • 7
    Neopterin production, tryptophan degradation, and mental depression—What is the link?
    • 186
    Preliminary findings of antistreptococcal antibody titers and basal ganglia volumes in tic, obsessive-compulsive, and attention deficit/hyperactivity disorders.
    • 192
    • Highly Influential
    • PDF
    Elevated plasma kynurenine in Tourette syndrome.
    • 19