Plasma kinetics and urinary excretion of primaquine in man.

@article{Greaves1980PlasmaKA,
  title={Plasma kinetics and urinary excretion of primaquine in man.},
  author={John Greaves and David Alan Price Evans and Herbert M. Gilles and K Alexander Fletcher and Danai Bunnag and T Harinasuta},
  journal={British journal of clinical pharmacology},
  year={1980},
  volume={10 4},
  pages={399-404}
}
1 The kinetics of primaquine have been studied in twenty volunteers after single and multiple dose regimes. 2 The kinetic parameters were similar in glucose-6-phosphate dehydrogenase (G6PD) normal Thais, G6PD deficient Thais and in Caucasians. 3 The Caucasian subjects showed about 1% of the dose was excreted in the urine. 4 The kinetic parameters obtained from multiple dose studies in Thais were very similar to those obtained from single dose studies in Thais. 

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Treatment and Prevention of Malaria

Milestones in Drug Therapy • 2012
View 4 Excerpts
Highly Influenced

Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation.

Drug metabolism and disposition: the biological fate of chemicals • 2014
View 1 Excerpt

Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I.

The American journal of tropical medicine and hygiene • 2006
View 1 Excerpt

Pharmacokinetics of primaquine in healthy volunteers.

The Southeast Asian journal of tropical medicine and public health • 1991

Pharmacokinetics of primaquine in patients withP. Vivax malaria

European Journal of Clinical Pharmacology • 1986
View 1 Excerpt

Similar Papers

Loading similar papers…