Plasma kinetics and efficacy of oral megazol treatment in Trypanosoma brucei brucei-infected sheep.

@article{Boda2004PlasmaKA,
  title={Plasma kinetics and efficacy of oral megazol treatment in Trypanosoma brucei brucei-infected sheep.},
  author={Caroline Boda and Bertin Enanga and H{\'e}l{\`e}ne Dumet and G{\'e}rard Chauvi{\`e}re and François J Labrousse and Claude Couquet and Sylvie Saivin and Georges Houin and Jacques P{\'e}ri{\'e} and Michel Dumas and Bernard Bouteille},
  journal={Veterinary parasitology},
  year={2004},
  volume={121 3-4},
  pages={213-23}
}
Experimentally infected sheep have been previously developed as an animal model of trypanosomosis. We used this model to test the efficacy of megazol on eleven Trypanosoma brucei brucei-infected sheep. When parasites were found in blood on day 11 post-infection, megazol was orally administered at a single dose of 40 or 80mg/kg. After a transient… CONTINUE READING