Plasma interleukin-8 as a potential predictor of mortality in adult patients with severe traumatic brain injury.

@article{Gopevi2007PlasmaIA,
  title={Plasma interleukin-8 as a potential predictor of mortality in adult patients with severe traumatic brain injury.},
  author={Aleksandar Vu{\vc}i{\'c} Marinko Gop{\vc}evi{\'c} and Branka Mazul-Sunko and Jasminka Marout and Ante Sekuli{\'c} and Nata{\vs}a Antoljak and Mladen {\vS}iranovi{\'c} and Zeljko Ivanec and Marko M. Margaritoni and Miroslav Bekavac-Be{\vs}lin and Neven Zarkovic},
  journal={The Tohoku journal of experimental medicine},
  year={2007},
  volume={211 4},
  pages={
          387-93
        }
}
Because of complex pathophysiology and severe consequences, traumatic brain injuries (TBI) are an important medical problem. Pathophysiology of TBI includes local and systemic stress response, in which interleukin-8 (IL-8) is considered as a key mediator of neuroinflammation. However, prognostic relevance of IL-8 measurement in adult patients with severe TBI is not certain. Therefore, IL-8 was determined in blood samples from central venous and jugular bulb catheter and in cerebrospinal fluid… CONTINUE READING

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