Plasma glutathione peroxidase activity is reduced in haemodialysis patients.

@article{Roxborough1999PlasmaGP,
  title={Plasma glutathione peroxidase activity is reduced in haemodialysis patients.},
  author={Heather Roxborough and Caroline Mercer and Dorothy McMaster and Alexander Peter Maxwell and Ian S Young},
  journal={Nephron},
  year={1999},
  volume={81 3},
  pages={278-83}
}
Cardiovascular disease is the major cause of morbidity and mortality in patients with end-stage renal failure. Increased free radical production and antioxidant depletion may contribute to the greatly increased risk of atherosclerosis in these patients. Glutathione peroxidase (GPX) is an important antioxidant, the plasma form of which is synthesized mainly in the kidney (eGPX). The aim of this study was to assess the activity of eGPX in patients with end-stage renal failure on haemodialysis… CONTINUE READING
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