Plasma glutamate levels, lymphocyte reactivity and death rate in patients with bronchial carcinoma

@article{Eck1989PlasmaGL,
  title={Plasma glutamate levels, lymphocyte reactivity and death rate in patients with bronchial carcinoma},
  author={H. -P. Eck and Peter Drings and Wulf Dr{\"o}ge},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={1989},
  volume={115},
  pages={571-574}
}
Elevated glutamate concentrations are commonly observed in patients with advanced carcinoma, and glutamate was recently found to inhibit the membrane transport of cystine and to impair the function of macrophages and lymphocytes in vitro. We therefore investigated the possibility that elevated plasma glutamate levels may be quantitatively correlated with reduced lymphocyte reactivity and an impaired host response to the tumor. Here we report the results of a study on patients with bronchial… CONTINUE READING

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Influence of the extracellular glutamate concentration on the intracellular cyst(e)ine concentration in macrophages and on the capacity to release cysteine

  • Eck H-P
  • Biol Chem Hoppe Seyler
  • 1989

Ver~inderungen des Immunsystems bei Patienten mit Bronchialkarzinom

  • Manke H-G, P Aulenbacher
  • Drings P,
  • 1985

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