Plasma glial fibrillary acidic protein levels in children with sickle cell disease.

@article{Savage2011PlasmaGF,
  title={Plasma glial fibrillary acidic protein levels in children with sickle cell disease.},
  author={William J. Savage and Emily A Barron-Casella and Zongming Fu and Pratima Dulloor and Lisa M. Williams and Barbara J. Crain and Desir{\'e}e A. White and Jacky M. Jennings and Jennifer E Van Eyk and Michael Rutledge DeBaun and Allen E. Everett and James F. Casella},
  journal={American journal of hematology},
  year={2011},
  volume={86 5},
  pages={
          427-9
        }
}
To determine if glial fibrillary acidic protein (GFAP) is associated with brain injury in children with sickle cell disease (SCD), we measured plasma GFAP among cross-sectional groups of unselected children with SCD, subsets of children with SCD and normal brain MRI or MRI evidence of cerebral infarct, healthy pediatric controls, and adults with brain injury. Children with SCD had higher plasma GFAP than healthy pediatric controls (mean concentrations 0.14 ± 0.37 vs. 0.07 ± 0.08 ng/mL; P 5 0… CONTINUE READING

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