Plasma ghrelin and obestatin levels are increased in spontaneously hypertensive rats.

@article{Li2010PlasmaGA,
  title={Plasma ghrelin and obestatin levels are increased in spontaneously hypertensive rats.},
  author={Zhao-feng Li and Zhi-fu Guo and Jiang Cao and Jian-qiang Hu and Xianxian Zhao and Rong-liang Xu and Xin-miao Huang and Yong-wen Qin and Xing Bang Zheng},
  journal={Peptides},
  year={2010},
  volume={31 2},
  pages={297-300}
}
Obestatin, encoded by the same gene as ghrelin, was first described as a physiological opponent of ghrelin. We investigated fasting plasma ghrelin and obestatin levels in spontaneously hypertensive rats and Wistar-Kyoto rats. We found that ghrelin levels, obestatin levels and the ratio of ghrelin to obestatin were significantly higher in spontaneously hypertensive rats than Wistar-Kyoto rats. Systolic blood pressure and diastolic blood pressure were positively correlated; however, heart period… CONTINUE READING

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