Plasma fucosyltransferase as an indicator of imminent blastic crisis.

  title={Plasma fucosyltransferase as an indicator of imminent blastic crisis.},
  author={I Shah-Reddy and David H Kessel and T. H. Chou and Ila Mirchandani and U Khilanani},
  journal={American journal of hematology},
  volume={12 1},
Plasma fucosyltransferase activity was evaluated as an indicator of an impending blastic transformation in 25 patients with chronic granulocytic leukemia (CGL). Fifteen age-and sex-matched controls were also studied. The level of enzyme activity was significantly higher in the plasma of patients with blastic transformation (1,630 +/- 570 units) compared with steady chronic granulocytic leukemia (509 +/- 110 units) and normal controls (354 +/- 57 units). In three patients with CGL, a rise in… CONTINUE READING

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