Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification.

BACKGROUND A relation between low folate status and depression has been recognized since the 1960s. Since 1998, flour in the United States has been fortified with folic acid, and the prevalence of folate deficiency has decreased dramatically. OBJECTIVE We investigated whether, in this era of folic acid fortification, low folate status is a determinant of… CONTINUE READING