Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.

@article{Danesh2005PlasmaFL,
  title={Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.},
  author={John Danesh and Sarah Lewington and Simon G Thompson and Gordon D. O. Lowe and Rory Collins and John B. Kostis and A. C. Wilson and Aaron R. Folsom and K. K. Wu and Michal Benderly and Uri Goldbourt and Johann Willeit and Stefan Kiechl and John W. G. Yarnell and Peter M. Sweetnam and Peter C. Elwood and Mary Cushman and Bruce M. Psaty and Russell P. Tracy and Anne Tybjaerg-hansen and Frits Haverkate and Moniek P. M. de Maat and Francis Gerry R Fowkes and A. J. Lee and Felicity B Smith and Veikko V Salomaa and Kennet Harald and Renata Rasi and Elina M. Vahtera and Pekka Jousilahti and Juha Pekkanen and Ralph B. D'Agostino and William B. Kannel and Peter W. F. Wilson and Geoffrey H Tofler and Carmen Luisa Arocha-Pi{\~n}ango and A. Rodriguez-Larralde and Elena Nagy and Mercedes Elena Mijares and Ra{\'u}l A Espinosa and E Rodriquez-Roa and Elena Ryder and Mar{\'i}a Diez‐Ewald and Gilberto Campos and Virginia Fern{\'a}ndez and Enrique Torres and Roberto Marchioli and Franco Valagussa and Annika Rosengren and Lars W. Wilhelmsen and Georgios Lappas and Henry Eriksson and Peter Cremer and Dorothea Nagel and J. David Curb and Beatriz L. Rodr{\'i}guez and Katsuhiko Yano and Jukka T. Salonen and Kristiina Nyyssönen and Tomi-Pekka Tuomainen and Bo Hedblad and Peter Lind and Hannelore Loewel and Wolfgang Koenig and Tom W. Meade and Jackie A. Cooper and Bianca L. De Stavola and C. Knottenbelt and George J. Miller and Kenneth A. Bauer and Robert D. Rosenberg and S. Sato and Akihiko Kitamura and Yoshihiko Naito and Timo Palosuo and Pierre Ducimetiere and Philippe Amouyel and Dominique Arveiler and Alun E. Evans and Jean Ferri{\`e}res and I Juhan-vague and Annie Bingham and Helmut Schulte and Gerd Assmann and Bernard Cantin and Beno{\^i}t Lamarche and Jean-Pierre Despr{\'e}s and Gilles R. Dagenais and Hugh Tunstall-Pedoe and Mark Woodward and Yoav Ben-Shlomo and George Davey Smith and V. Palmieri and Jeunliang Yeh and Alicja Regina Rudnicka and Paul M. Ridker and Francesco Rodeghiero and Alberto Tosetto and James Shepherd and Ian Ford and Michele Robertson and Eric J. Brunner and M J Shipley and Edith J. M. Feskens and Daan Kromhout and Alfred Dickinson and Belinda K Ireland and Kelsey Juzwishin and Stephen Kaptoge and Sarah Lewington and Anis Memon and Nadeem Sarwar and Matthew Walker and Jeremy G. Wheeler and Ian R. White and Angela M. Wood},
  journal={JAMA},
  year={2005},
  volume={294 14},
  pages={
          1799-809
        }
}
CONTEXT Plasma fibrinogen levels may be associated with the risk of coronary heart disease (CHD) and stroke. OBJECTIVE To assess the relationships of fibrinogen levels with risk of major vascular and with risk of nonvascular outcomes based on individual participant data. DATA SOURCES Relevant studies were identified by computer-assisted searches, hand searches of reference lists, and personal communication with relevant investigators. STUDY SELECTION All identified prospective studies… 

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The Fibrinogen Studies Collaboration will aim to characterize more precisely than has previously been possible the strength and shape of the age- and sex-specific associations of plasma fibr inogen with coronary heart disease and, where data are sufficient, with other vascular diseases.

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