Plasma extravasation by chemical mediators in rat skin and trachea: a role of neurogenic agents on tracheal edema formation.

@article{Morimoto1989PlasmaEB,
  title={Plasma extravasation by chemical mediators in rat skin and trachea: a role of neurogenic agents on tracheal edema formation.},
  author={Hiroshi Morimoto and Toshihide Fujii and Hideki Senoh},
  journal={Japanese journal of pharmacology},
  year={1989},
  volume={49 3},
  pages={389-95}
}
The plasma extravasation inducing activities of several chemical mediators (allergic agents: histamine, leukotriene C4 (LTC4) and platelet activating factor (PAF); neurogenic agents: substance P, capsaicin and carbachol) have been investigated and characterized in rat skin and trachea. Substance P, histamine, LTC4 and PAF induced dose-dependent plasma… CONTINUE READING