Plasma exchange in the long-term management of Waldenström's macroglobulinemia.

@article{Buskard1977PlasmaEI,
  title={Plasma exchange in the long-term management of Waldenstr{\"o}m's macroglobulinemia.},
  author={Noel Buskard and D. A. G. Galton and John M. Goldman and Eva Maria Kohner and C F Grindle and Dr. Leonard Newman and K W Twinn and Ray M. Lowenthal},
  journal={Canadian Medical Association journal},
  year={1977},
  volume={117 2},
  pages={135-7}
}
Two patients with Waldenström's macroglobulinemia (WM), which had become resistant to cytotoxic drugs, were treated for features of the hyperviscosity syndrome by repeated plasma exchange with the continuous-flow blood-cell separator over periods of 36 and 28 months, respectively. After four initial weekly plasma exchanges the procedure was carried out every 4 to 6 weeks and both patients tolerated it well. Relative viscosity of the serum was maintained within the normal range in one patient… CONTINUE READING

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