Plasma endocannabinoid levels in multiple sclerosis.

  title={Plasma endocannabinoid levels in multiple sclerosis.},
  author={Lucie Jean-Gilles and Shujun Feng and Christopher R. Tench and V. Chapman and David A. Kendall and David A. Barrett and Cris S. Constantinescu},
  journal={Journal of the neurological sciences},
  volume={287 1-2},
BACKGROUND Multiple sclerosis (MS) is a chronic inflammatory disease of the CNS. Therapies that affect the endocannabinoid (EC) system may have immunomodulatory, symptomatic and neuroprotective effects. AIM The aim of this study was to determine how levels of EC and related compounds are altered in MS. METHODS Plasma and whole blood were collected from 24 MS patients (10 relapsing-remitting (RR); 8 secondary-progressive (SP); 6 primary-progressive (PP); 19 females; 25-66 years) and 17… CONTINUE READING
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