Plasma endocan levels associate with inflammation, vascular abnormalities, cardiovascular events, and survival in chronic kidney disease.

@article{Yilmaz2014PlasmaEL,
  title={Plasma endocan levels associate with inflammation, vascular abnormalities, cardiovascular events, and survival in chronic kidney disease.},
  author={Mahmut Ilker Yilmaz and Dimitrie Siriopol and Mutlu Sağlam and Yasemin G{\"u}lcan Kurt and Hilmi Umut Unal and Tayfun Eyileten and M. Sabri Gok and Hakki Cetinkaya and Yusuf Oğuz and Sebahattin Sari and A. Gural Vural and Irina Mititiuc and Adrian Constantin Covic and Mehmet Kanbay},
  journal={Kidney international},
  year={2014},
  volume={86 6},
  pages={1213-20}
}
Plasma endocan levels are elevated in a large number of diseases, and may reflect endothelial cell dysfunction. There are currently no data on endocan in patients with chronic kidney disease (CKD). Therefore, we measured plasma endocan in 251 patients with CKD (stage 1-5) and 60 control individuals. Plasma endocan concentrations correlated with estimated glomerular filtration rate (eGFR), different markers of inflammation (pentraxin 3 and high-sensitivity C-reactive protein), and vascular… CONTINUE READING
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