Plasma drug and homovanillic acid levels in psychotic patients receiving neuroleptics.

@article{Harris1984PlasmaDA,
  title={Plasma drug and homovanillic acid levels in psychotic patients receiving neuroleptics.},
  author={Peter Harris and Susan J. Brown and Matthew J. Friedman and N. G. Bacopoulos},
  journal={Biological psychiatry},
  year={1984},
  volume={19 6},
  pages={849-60}
}
Plasma neuroleptic and homovanillic acid (HVA) levels are reported for a group of psychotic subjects exhibiting clinical improvement in response to neuroleptic medication. Clinically effective plasma neuroleptic levels, measured by a radioreceptor assay and expressed as either nanomolar concentration of parent drug or as haloperidol equivalents, were different for the seven neuroleptics tested. Plasma HVA, measured by high-pressure liquid chromatography with electrochemical detection (LCEC… CONTINUE READING