Plasma dexamethasone and cortisol levels in depressed outpatients.

  title={Plasma dexamethasone and cortisol levels in depressed outpatients.},
  author={Gregory M. Asnis and Jan M Friedman and Andrew H. Miller and Naveed Iqbal and E. S. Lo and Thomas B. Cooper and Uriel M Halbreich and Cuauhtemoc Lemus and H M van Praag and Eileen Rubinson},
  journal={Journal of affective disorders},
  volume={16 1},
We investigated the 1-mg dexamethasone suppression test (DST) in 41 outpatients with major depressive disorder assessing the role of dexamethasone blood level, age and basal cortisol on DST results. Non-suppressors (approximately 25% of patients) had lower dexamethasone levels, and post-dexamethasone cortisol was negatively correlated with plasma dexamethasone; these findings were more significant after covarying out age and basal cortisol, factors that were also significantly associated to non… CONTINUE READING

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