Plasma-derived and synthetic high-density lipoprotein inhibit tissue factor in endothelial cells and monocytes.

Abstract

HDL (high-density lipoproteins) exert anti-thrombotic activities by preventing platelet adhesion and activation and by stimulating the protein C pathway and fibrinolysis. The aim of the present study was to assess the effect of plasma-derived and synthetic HDL on endothelial and monocyte expression of TF (tissue factor), the primary initiator of coagulation… (More)
DOI: 10.1042/BJ20151000

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