Plasma concentrations of phyto-oestrogens in Japanese men

@article{Adlercreutz1993PlasmaCO,
  title={Plasma concentrations of phyto-oestrogens in Japanese men},
  author={Herman C T Adlercreutz and H. Markkanen and Shigeru Watanabe},
  journal={The Lancet},
  year={1993},
  volume={342},
  pages={1209-1210}
}
A low mortality from prostatic cancer is found in Japanese men consuming a low-fat diet with high content of soy products, a rich source of isoflavonoids. We therefore assayed four isoflavonoids in plasma of 14 Japanese and 14 Finnish men. The geometric mean plasma total individual isoflavonoid levels were 7 to 110 times higher in the Japanese than in the Finnish men. Genistein, a tyrosine kinase inhibitor, occurred in the highest concentration (geometric mean 276 nmol/L). We hypothesise that… CONTINUE READING
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