Plasma concentration of malaria parasite-derived macrophage migration inhibitory factor in uncomplicated malaria patients correlates with parasitemia and disease severity.

@article{Han2010PlasmaCO,
  title={Plasma concentration of malaria parasite-derived macrophage migration inhibitory factor in uncomplicated malaria patients correlates with parasitemia and disease severity.},
  author={Cong Cong Han and Yahui Lin and Guang Liang Shan and Zaixing Zhang and Xiaodong Sun and Zhensheng Wang and Chunyan Wei and Yan Deng and Lianhui Zhang and Lingyi Bu and Dingding Shao and Heng Wang},
  journal={Clinical and vaccine immunology : CVI},
  year={2010},
  volume={17 10},
  pages={
          1524-32
        }
}
Host macrophage migration inhibitory factor (MIF) has been implicated in the pathogenesis of malaria infections. Several Plasmodium parasite-derived MIFs were identified to have the potential to regulate host immune response. However, the role of Plasmodium MIFs in the immunopathogenesis of malaria infection and the relationships between these mediators and inflammatory cytokines remained unclear. In this study, we have investigated two Plasmodium MIFs in peripheral blood of uncomplicated… CONTINUE READING

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