Plasma citrulline: A marker of enterocyte mass in villous atrophy-associated small bowel disease.

@article{Crenn2003PlasmaCA,
  title={Plasma citrulline: A marker of enterocyte mass in villous atrophy-associated small bowel disease.},
  author={Pascal Crenn and Kouroche Vahedi and Anne Lavergne-Slove and Luc A Cynober and C Matuchansky and Bernard Messing},
  journal={Gastroenterology},
  year={2003},
  volume={124 5},
  pages={1210-9}
}
BACKGROUND & AIMS Plasma citrulline, a nonprotein amino acid produced by enterocytes, was suggested as a marker of remnant enterocyte mass in patients with short bowel. Our objective was to evaluate citrulline as a marker of severity and extent of villous atrophy in patients without intestinal resection. METHODS Forty-two patients with celiac disease and 10 patients with non-celiac villous atrophy disease were studied by plasma postabsorptive citrulline and biological dosages, biopsies of… CONTINUE READING

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