Plasma cholesterol lowering action of bile acid binding polymers in experimental animals.

@article{Tennent1960PlasmaCL,
  title={Plasma cholesterol lowering action of bile acid binding polymers in experimental animals.},
  author={D M Tennent and Herbert Siegel and M. E. Zanetti and G W Kuron and W H Ott and Franz Wolf},
  journal={Journal of lipid research},
  year={1960},
  volume={1},
  pages={469-73}
}
Feeding of bile acid binding polymeric organic bases inhibited cholesterol rise and aortic. plaque formation in cholesterol-fed cockerels, lowered plasma cholesterol concentrations in normocholesterolemic cockerels and dogs, and increased fecal bile acid and sterol output in a dog. In experiments lasting as long a~ one year these substances have not produced visible toxic effects. They are thought to act by binding the bile acids in the intestinal tract. 

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Physiological Chemisty of the Bile

  • King, J E.
  • Medical Biochemistry. London,
  • 1951
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