Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C.

@article{Butera2005PlasmaCL,
  title={Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C.},
  author={David Butera and Svetlana Marukian and Amy E Iwamaye and Edgardo Hembrador and Thomas J. Chambers and Adrian M Di Bisceglie and Edgar D. Charles and Andrew H. Talal and I M for the New Paradigm of HCV Therapy Meeting Part Jacobson and Charles M. Rice and Lynn B. Dustin},
  journal={Blood},
  year={2005},
  volume={106 4},
  pages={1175-82}
}
Chronic infection with the hepatitis C virus (HCV) is associated with failures of T-cell-mediated immune clearance and with abnormal B-cell growth and activation. We examined the levels of chemokines that bind to CXC chemokine receptor 3 (CXCR3) to determine whether such chemokines might play a role in the failure of the immune system to clear HCV infection. Elevations in CXC ligand 9 (CXCL9), CXCL10, and CXCL11 were observed in all patients with HCV. CXCR3 expression was increased… CONTINUE READING
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