Plasma cell-rich acute rejections in living-related kidney transplantation: a clinicopathological study of 50 cases.

@article{Abbas2015PlasmaCA,
  title={Plasma cell-rich acute rejections in living-related kidney transplantation: a clinicopathological study of 50 cases.},
  author={Khawar Abbas and Muhammed Mubarak and Mirza Naqi Zafar and Tahir Aziz and Haider Abbas and Rana Muzaffar and Syed A.H. Rizvi},
  journal={Clinical transplantation},
  year={2015},
  volume={29 9},
  pages={835-41}
}
BACKGROUND Acute rejections (ARs) with plasma cell-rich infiltrates (PCARs) are associated with poor outcomes. PATIENTS AND METHODS Between February 2012 and December 2013, 1630 dysfunctional renal graft biopsies were performed. Of these, 50 (3%) showed PCAR. ARs with >10% plasma cells were defined as PCAR. Human leukocyte antigen (HLA) antibodies were tested in historic sera and at the time of PCAR. Treatment for PCAR comprised methylprednisolone, antithymocyte globulin, plasmapheresis, and… CONTINUE READING

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