Plasma catabolism of human apolipoprotein E isoproteins: lack of conversion of the doubly sialylated form to the asialo form in plasma.

@article{Ghiselli1986PlasmaCO,
  title={Plasma catabolism of human apolipoprotein E isoproteins: lack of conversion of the doubly sialylated form to the asialo form in plasma.},
  author={Giancarlo Ghiselli and Yitzhak Beigel and Masaaki Soma and Antonio M. Gotto},
  journal={Metabolism: clinical and experimental},
  year={1986},
  volume={35 5},
  pages={399-403}
}
Apolipoprotein E (apoE) circulates as a mixture of sialylated and asialylated forms. In this study the catabolic fate and the plasma turnover rate of the different apoE forms have been investigated in vivo in humans. Asialo apoE (E) and doubly sialylated apoE (Ess) were isolated by preparative isoelectrofocusing from the VLDL of subjects homozygous for the… CONTINUE READING