Plasma arginine and ornithine are the main citrulline precursors in mice infused with arginine-free diets.

Abstract

Dietary arginine is the main dietary precursor for citrulline synthesis, but it is not known if other precursors can compensate when arginine is absent in the diet. To address this question, the contributions of plasma and dietary precursors were determined by using multitracer protocols in conscious mice infused i.g. either an arginine-sufficient diet [Arg… (More)
DOI: 10.3945/jn.110.125377

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