Plasma appearance and distribution of astaxanthin E/Z and R/S isomers in plasma lipoproteins of men after single dose administration of astaxanthin.

@article{sterlie2000PlasmaAA,
  title={Plasma appearance and distribution of astaxanthin E/Z and R/S isomers in plasma lipoproteins of men after single dose administration of astaxanthin.},
  author={Marianne {\O}sterlie and Bj{\o}rn Bjerkeng and Synn∅ve Liaaen-Jensen},
  journal={The Journal of nutritional biochemistry},
  year={2000},
  volume={11 10},
  pages={
          482-90
        }
}
Appearance, pharmacokinetics, and distribution of astaxanthin E/Z and R/S isomers in plasma and lipoprotein fractions were studied in 3 middle-aged male volunteers (37-43 years) after ingestion of a single meal containing a 100 mg dose of astaxanthin. The astaxanthin source consisted of 74% all-E-, 9% 9Z-, 17% 13Z-astaxanthin (3R,3'R-, 3R,3'S; meso-, and 3S,3'S-astaxanthin in a 1:2:1 ratio). The plasma astaxanthin concentration--time curves were measured during 72 hr. Maximum levels of… Expand
Plasma appearance of unesterified astaxanthin geometrical E/Z and optical R/S isomers in men given single doses of a mixture of optical 3 and 3'R/S isomers of astaxanthin fatty acyl diesters.
TLDR
The results indicate that a selective process increase the relative proportion of astaxanthin Z-isomers compared to the all-E-astaxanth in blood before uptake in blood and that the astxanthin esters are hydrolyzed selectively during absorption. Expand
Plasma appearance and tissue accumulation of non-esterified, free astaxanthin in C57BL/6 mice after oral dosing of a disodium disuccinate diester of astaxanthin (Heptax).
TLDR
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TLDR
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TLDR
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Apparent digestibility coefficients and accumulation of astaxanthin E/Z isomers in Atlantic salmon (Salmo salar L.) and Atlantic halibut (Hippoglossus hippoglossus L.).
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  • 2000
TLDR
The higher ADC of astaxanthin in halibut than Atlantic salmon may be explained by lower feed intake in Halibut, and the lower retention of astxanthin by a higher capacity to transform astax Anthraxanthin metabolically. Expand
Safety assessment of astaxanthin from Haematococcus pluvialis: Acute toxicity, genotoxicity, distribution and repeat-dose toxicity studies in gestation mice.
TLDR
Administration of astaxanthin from H. pluvialis throughout pregnancy had no adverse effect on mice, and during pregnancy, the liver accumulated the highest content of astrixanthin, while the eye exhibited the least. Expand
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