Plasma and milk kinetic of eprinomectin and moxidectin in lactating water buffaloes (Bubalus bubalis).

@article{Dupuy2008PlasmaAM,
  title={Plasma and milk kinetic of eprinomectin and moxidectin in lactating water buffaloes (Bubalus bubalis).},
  author={Jacques Dupuy and J. F. Sutra and Michel Alvinerie and Laura Rinaldi and V. Veneziano and Laura Mezzino and Saverio Pennacchio and Giuseppe Cringoli},
  journal={Veterinary parasitology},
  year={2008},
  volume={157 3-4},
  pages={284-90}
}
The pharmacokinetics and mammary excretion of moxidectin and eprinomectin were determined in water buffaloes (Bubalus bubalis) following topical administration of 0.5mgkg(-1). Following administration of moxidectin, plasma and milk concentrations of moxidectin increased to reach maximal concentrations (C(max)) of 5.46+/-3.50 and 23.76+/-16.63ngml(-1) at T(max) of 1.20+/-0.33 and 1.87+/-0.77 days in plasma and milk, respectively. The mean residence time (MRT) were similar for plasma and milk (5… CONTINUE READING
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